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2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide

Name 2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide
CAS NO. 302964-24-5
Molecular Formula C11H10ClN3OS Molecular Weight 267.73
MDL No. MFCD10000630 EINECS 1806241-263-5
M.P. 208.0 ~ 212.0 °C B.P. 362.0±37.0 °C(Predicted)
Density 1.474g/cm3(Predicted) Refractive Index N.A.

F.P.

N.A.

Storage condition

under inert gas (nitrogen or Argon) at 2–8 °C

 
Appearance white to light yellow crystal powder
Purity 98%
Application It is the precursor for the synthesis of Dasatinib (D193600), which is a protein tyrosine kinase inhibitor and the precursor of 2-aminothiazole-5-carboxylic acid benzamide derivatives. It is an effective selective antineoplastic drugs.

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